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In her recent article in the University of Chicago’s Celiac Disease Center newsletter, “Impact,” Dr. Carol Semrad seeks to clarify the important steps needed to accurately diagnose celiac disease. Traditionally, celiac disease has been diagnosed by duodenal (small bowel) biopsy, however, there are a number of different ailments and conditions that can lead to small…

Considering the rising number of cases of celiac disease, and its extremely detrimental effects on childhood development, leading to malabsorption and failure to thrive, it is becoming more necessary to find a means to properly diagnose young children.

Those who have the standard clinical symptoms of celiac disease, such as sensitivity to gluten, irritability, abdominal pain, or a positive blood test, may undergo an endoscopy to confirm their diagnosis. During the procedure, doctors take samples of tissue (a biopsy) from the small intestine to see if there is damage or flattening of villi. Under a microscope, a…